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Lattice Formation of Clathrin

Client:

Justin Taraska (NIH/NHLBI) et al.,

Project Description:

Dozens of proteins capture, polymerize and reshape the clathrin lattice during clathrin-mediated endocytosis (CME). Six key observed structural phenomena of clathrin-associated proteins are hypothesized to be occurring during different stages of pit development. The illustration supports the finding that endocytic proteins distribute into distinct spatial zones in relation to the edge of the clathrin lattice.

Manuscript title:

Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells.
Nat Cell Biol. 2017 April;19(4):352-361
PMID: 28346440
PubMed
Illustrator: Ethan Tyler

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