ACS Chemical Biology cover

Christophe Marchand (NIH/NCI)
Project description:
Surface models exported from the Protein Data Base 3D were employed to create this artist interpretation of the selective Inhibition of human tyrosyl-DNA phosphodiesterase 2 (TDP2) by a deazaflavin derivative.
Manuscript title:
Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2
ACS Chem Biol. 2016 Jul 15;11(7)
PMID: 27128689
Illustrator: David Blum