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ACS Chemical Biology cover

Client:

Christophe Marchand (NIH/NCI)

Project description:

Surface models exported from the Protein Data Base 3D were employed to create this artist interpretation of the selective Inhibition of human tyrosyl-DNA phosphodiesterase 2 (TDP2) by a deazaflavin derivative.

Manuscript title:

Deazaflavin Inhibitors of Tyrosyl-DNA Phosphodiesterase 2 (TDP2) Specific for the Human Enzyme and Active against Cellular TDP2
ACS Chem Biol. 2016 Jul 15;11(7)
PMID: 27128689
PubMed
Illustrator: David Blum

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